Therapeutic Keratopigmentation: Cosmetic and Functional Outcomes and Complications.
Seyed Javad Hashemian1 *, Sepehr Roozdar 2
- Iran University of Medical Sciences and Iranian Eye Clinic
- Iran University of Medical Sciences
Abstract: To assess safety, efficacy and complications of therapeutic femtosecond laser assisted (FA) and manual automated (MA) keratopigmentation (KTP) using micronized mineral pigments.
Methods: KTP was performed in 85 eyes of 85 patients with moderate to severe visual disabilities (range: 20/80 to NLP) related to various etiologies causing corneal scar or iris abnormalities. 36 eyes were treated by FA-KTP, 46 eyes by MA-KTP and 3 eyes using combined MA and FA-KTP. The cosmetic outcome, patient satisfaction, stability of pigmentation, and presence of any related complications are reported. The mean follow-up period was 10.8 months (range: 1-53 months).
Results: 48 males and 37 females were included. The mean age was 37.8 ± 14.25 (range: 14-77). In total, 68 of 85 patients (80%) reported cosmetic satisfaction within the follow-up period. 74% of MA-KTP group (34 out of 46 patients), 86% of FA-KTP group (31 out of 36 patients) and 100% of combined group (3 patients) were satisfied with their cosmetic outcome. 12 eyes of MA-KTP (26%) and 5 eyes of FA-KTP group (14%) required additional KTP procedures due to color fading and cosmetic unsatisfaction. Post-operative symptoms were photophobia (28%), tearing (24%) and pain (8%). Photophobia and tearing were more common in MA-KTP group. Post-operative complications were dry eye (6%), delayed epithelial healing (2%) and microbial keratitis (1%).
Conclusion: FA-KTP and MA-KTP using micronized mineral pigments are safe and efficient surgical techniques for the management of cosmetic and visual disturbances caused by iris abnormalities and cosmetic issues related to corneal scars.
